fentanyl transdermal and pentobarbital both improve sedation. Keep away from or Use Alternate Drug. Limit use to patients for whom different therapy alternatives are inadequate
pentobarbital will reduce the level or impact of dienogest/estradiol valerate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Women should not decide on estradiol valerate/dienogest as their contraceptive though making use of strong CYP3A4 inducers resulting from possible decrease in contraceptive efficacy.
Hypnotic doses of such barbiturates tend not to look to significantly impair uterine action during labor; entire anesthetic doses of barbiturates lower the drive and frequency of uterine contractions; administration of sedative-hypnotic barbiturates to the mom during labor could lead to respiratory melancholy during the newborn
Aged or debilitated individuals may respond to barbiturates with marked melancholy, enjoyment, and confusion; in a few sufferers, barbiturates continuously make pleasure in lieu of despair
pentobarbital will lower the level or effect of conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital will lower the level or impact of etravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
Contraindicated (1)pentobarbital will decrease the extent or outcome of elbasvir/grazoprevir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindicated (one)pentobarbital will minimize the level or outcome of roflumilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will minimize the level or outcome of eplerenone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
pentobarbital will reduce the level or impact of budesonide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will minimize the extent or influence of darifenacin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital get more info will decrease the extent or effect of lefamulin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Keep away from coadministration of lefamulin with sturdy or reasonable CYP3A inducers Except if the reward outweighs hazards. Keep track of for reduced efficacy.
pentobarbital will decrease the extent or influence of methadone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the level or effect of parecoxib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Not known.